Description

Ponazuril is a triazine-based antiprotozoal agent, widely recognized for its potent efficacy against apicomplexan parasites. This high-purity compound is essential for the development of veterinary and research formulations targeting coccidiosis and equine protozoal myeloencephalitis (EPM). Key industries that rely on this active pharmaceutical ingredient include veterinary pharmaceutical manufacturers, animal health research institutions, and suppliers of fine chemicals for therapeutic applications.

Application

• Veterinary Pharmaceuticals: Primary active ingredient in oral pastes and formulations for the treatment of Equine Protozoal Myeloencephalitis (EPM) caused by Sarcocystis neurona.
• Poultry Health: Used in research and development of anticoccidial agents to control coccidiosis in poultry farming operations.
• Companion Animal Medicine: Investigated for use in treating systemic protozoal infections in dogs and other companion animals.
• API Synthesis: Serves as a critical raw material (Active Pharmaceutical Ingredient) for GMP-certified manufacturers producing finished dosage forms.
• Research & Development: A standard reference compound in parasitology research for studying the efficacy and mechanism of action of triazine antiprotozoals.
• Aquaculture: Potential application in controlling protozoan parasites in farmed fish species.

Basic Information

Product Name	Ponazuril
CAS No.	69004-04-2
Molecular Formula	C17H14F3N3O5S
Molecular Weight	429.37 g/mol
Synonyms	1-Methyl-3-[3-methyl-4-[4-(trifluoromethoxy)phenoxy]phenyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; Toltrazuril sulfone; Toltrazuril sulfoxide; Bay Vi 9142; Compound 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-methyl-3-[3-methyl-4-[4-(trifluoromethoxy)phenoxy]phenyl]-; Marquisa® (brand name for equine formulation); Ponalrestat (historical, related research context).
EINECS	Contact for details

Quality Control

Our Ponazuril is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Quality assurance includes rigorous testing for identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (by HPLC), related substances, residual solvents, and heavy metals. We support compliance with GMP and relevant veterinary pharmacopoeia standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.