Description

3-Thiophenecarbonitrile, 2-Amino-5-Formyl- is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a formyl group on a thiophene-carbonitrile core, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or starting material for the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: The amino and nitrile groups allow for chelation to metal centers, useful in creating novel catalysts for asymmetric synthesis.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new heterocyclic chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Thiophenecarbonitrile, 2-Amino-5-Formyl-
CAS No.	68935-75-1
Molecular Formula	C6H4N2OS
Molecular Weight	152.17 g/mol
Synonyms	2-Amino-5-formyl-3-thiophenecarbonitrile; 5-Formyl-2-amino-3-thiophenecarbonitrile; 2-Amino-5-formylthiophene-3-carbonitrile; 3-Cyano-2-amino-5-formylthiophene; 2-Amino-5-formyl-3-cyanothiophene; 5-Formyl-2-aminothiophene-3-carbonitrile; 2-Amino-5-thiophenecarboxaldehyde-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonitrile, 2-Amino-5-Formyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.