Description

Methyl 4-Methyl-2-[(Trimethylsilyl)Amino]Pentanoate is a specialized organosilicon-protected amino acid ester, a key building block in advanced organic synthesis. Its value lies in providing a reactive yet protected amino group, enabling precise and efficient multi-step synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing peptide mimetics and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, especially in peptide and peptidomimetic research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative to control regioselectivity.
• Agrochemical Research: Serves as a key intermediate in the development of novel, high-performance pesticides and herbicides.
• Material Science: Employed in the synthesis of specialized polymers and silicon-containing hybrid materials with tailored properties.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Methyl 4-Methyl-2-[(Trimethylsilyl)Amino]Pentanoate
CAS No.	68835-83-6
Molecular Formula	C10H23NO2Si
Molecular Weight	217.38 g/mol
Synonyms	Methyl 2-[(Trimethylsilyl)amino]-4-methylpentanoate; 4-Methyl-2-[(trimethylsilyl)amino]pentanoic Acid Methyl Ester; L-Leucine, N-(trimethylsilyl)-, methyl ester; Methyl N-(trimethylsilyl)leucinate; TMS-Leucine-OMe; N-TMS-L-Leucine Methyl Ester; 2-[(Trimethylsilyl)amino]-4-methylpentanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Methyl-2-[(Trimethylsilyl)Amino]Pentanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.