Description

5-(Indol-3-Ylmethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is a versatile heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core structure, featuring both indole and Meldrum's acid moieties, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold's bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor in cycloaddition reactions, Knoevenagel condensations, and other transformations to create complex heterocycles.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of organic semiconductors, dyes, and photoresponsive polymers.
• Academic & R&D: Essential tool in methodological chemistry research for studying reaction mechanisms and developing new synthetic pathways.

Basic Information

Product Name	5-(Indol-3-Ylmethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
CAS No.	68588-31-8
Molecular Formula	C₁₅H₁₃NO₄
Molecular Weight	271.27 g/mol
Synonyms	5-[(1H-Indol-3-yl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione; 3-(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl-1H-indole; (Indol-3-ylmethylene)dimedone; Meldrum's acid indole derivative; 5-(1H-Indol-3-ylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
EINECS	Contact for details

Quality Control

Our 5-(Indol-3-Ylmethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.