Description

Lonomycin C is a potent polyether ionophore antibiotic isolated from *Streptomyces* species. This compound is valued for its ability to transport monovalent cations across biological membranes, making it a critical tool in biochemical and pharmacological research. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and agricultural chemistry sectors for studying ion transport mechanisms and as a lead compound for novel therapeutics. Lonomycin C CAS NO 68537-50-8 is supplied as a high-purity reference standard to ensure experimental reproducibility and reliability.

Application

• Biochemical Research: As a potassium ionophore to modulate intracellular ion concentrations and study cell signaling pathways.
• Pharmacology: Investigation of its antibiotic and potential anti-parasitic properties for drug discovery programs.
• Cell Biology: Used to induce apoptosis in cell culture studies by disrupting mitochondrial ion homeostasis.
• Veterinary Research: Exploration of its efficacy against coccidiosis and other veterinary pathogens.
• Agricultural Chemistry: Serves as a model compound for developing novel ionophore-based feed additives.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Lonomycin C
CAS No.	68537-50-8
Molecular Formula	C₄₆H₈₀O₁₄
Molecular Weight	857.1 g/mol
Synonyms	Lonomycin C; Lonomycin A3; Antibiotic X-14547A; Lasalocid A; Lasalocid; Avatec; Bovatec; Ionophore X-537A (related compound); 6-[7-[5-(5-Ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-2-hydroxy-3-methyl-6-oxo-2,3,3a,4,5,6,7,8-octahydro-1H-2-benzoxacyclododecin-9-yl]-4-hydroxy-2,5-dimethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-4,5-dihydro-2H-pyran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Lonomycin C is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and potency, meeting the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, and residual solvents is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.