Description

6,7,8,9-Tetrafluoro-3A,9B-Dihydro-1-Methyl-1H-Benz[G]Indole-2,3-Dicarboxylic Acid Dimethyl Ester is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a tetrafluorinated benzindole scaffold with reactive diester functionalities, enabling the construction of complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical R&D teams and specialty chemical manufacturers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its fluorinated indole core which can enhance bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms and heterocyclic structure contribute to improved efficacy and environmental profile.
• Material Science: Serves as a monomer or building block for creating specialty polymers, liquid crystals, or organic electronic materials with unique optical or electronic properties.
• Fluorine Chemistry: An essential substrate for further fluorination or functionalization reactions, enabling the exploration of new chemical space in medicinal and discovery chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new synthetic pathways involving fluorinated heterocycles.

Basic Information

Product Name	6,7,8,9-Tetrafluoro-3A,9B-Dihydro-1-Methyl-1H-Benz[G]Indole-2,3-Dicarboxylic Acid Dimethyl Ester
CAS No.	68464-43-7
Molecular Formula	C18H13F4NO4
Molecular Weight	383.30 g/mol
Synonyms	Dimethyl 6,7,8,9-tetrafluoro-1-methyl-3a,9b-dihydro-1H-benz[g]indole-2,3-dicarboxylate; 1-Methyl-6,7,8,9-tetrafluoro-3a,9b-dihydro-1H-benz[g]indole-2,3-dicarboxylic acid dimethyl ester; Benz[g]indole-2,3-dicarboxylic acid, 6,7,8,9-tetrafluoro-3a,9b-dihydro-1-methyl-, dimethyl ester; Tetrafluorobenz[g]indole diester.
EINECS	Contact for details

Quality Control

Our production of 6,7,8,9-Tetrafluoro-3A,9B-Dihydro-1-Methyl-1H-Benz[G]Indole-2,3-Dicarboxylic Acid Dimethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC/MS for solvent residue analysis, to ensure it meets the exacting standards required for research and scale-up. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.