Description

2-Toluidine-D7 is a deuterated isotopologue of 2-methylaniline, where seven hydrogen atoms are replaced with deuterium. This high-purity labeled compound is essential for applications requiring precise internal standards and metabolic pathway tracing in analytical chemistry. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors for advanced mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis of toluidine isomers and related aromatic amines.
• Metabolic Studies & Pharmacokinetics: Used as a stable isotope-labeled tracer to investigate the metabolic fate, absorption, and distribution of toluidine compounds in biological systems.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated solvent or shift reference in nuclear magnetic resonance spectroscopy due to its isotopic purity.
• Environmental Analysis: Employed in the detection and quantification of trace levels of aromatic amines in environmental samples like water and soil.
• Pharmaceutical Impurity Profiling: Used in method development and validation for identifying and quantifying process-related impurities and degradants.
• Chemical Reaction Mechanism Studies: Aids in elucidating reaction pathways and kinetics in synthetic organic chemistry through isotope effects.

Basic Information

Product Name	2-Toluidine-D7
CAS No.	68408-22-0
Molecular Formula	C7D7N
Molecular Weight	116.19 g/mol
Synonyms	2-Methylaniline-D7; o-Toluidine-D7; 2-Aminotoluene-D7; Deuterated o-Toluidine; (2H7)-2-Toluidine; 2-Methylbenzenamine-D7; o-Methylaniline-D7; 1-Amino-2-methylbenzene-D7
EINECS	Contact for details

Quality Control

Our 2-Toluidine-D7 is manufactured under strict quality protocols to ensure exceptional isotopic and chemical purity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % D), chemical purity by HPLC, and NMR conformity. We adhere to cGMP principles for consistent batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.