Description

(1S,6R)-4-Amino-2,5-Dioxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic oxabicyclo[4.1.0]heptene scaffold. This compound matters as a critical building block in the synthesis of complex, biologically active molecules, particularly in the development of novel antibiotics and enzyme inhibitors. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chiral synthon to enable the construction of new chemical entities with targeted therapeutic properties.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel β-lactam antibiotics and other complex pharmacophores.
• Antibiotic Research & Development: Serves as a core structural unit for developing next-generation antibacterial agents targeting resistant strains.
• Enzyme Inhibitor Synthesis: Used in constructing potent inhibitors for proteases and other enzymes relevant to disease pathways.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies due to its constrained, functionalized bicyclic system.
• Asymmetric Synthesis: Utilized as a chiral template or starting material in stereoselective chemical transformations.
• Fine Chemical Production: Incorporated into the manufacture of high-value, specialty chemicals for research and small-scale commercial applications.

Basic Information

Product Name	(1S,6R)-4-Amino-2,5-Dioxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxylic Acid
CAS No.	68330-49-4
Molecular Formula	C7H6N2O5
Molecular Weight	198.13 g/mol
Synonyms	4-Amino-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid; (1S,6R)-rel-4-Amino-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid; 7-Oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid, 4-amino-2,5-dioxo-, (1S,6R)-; 4-Amino-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid (enantiomer); Advanced β-lactam intermediate; Chiral oxabicycloheptene derivative.
EINECS	Contact for details

Quality Control

Our (1S,6R)-4-Amino-2,5-Dioxo-7-Oxabicyclo[4.1.0]Hept-3-Ene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.