Description

(+)-Isopinocampheylborane Tmeda Complex CAS NO 68297-74-5 is a highly valuable chiral organoboron reagent, specifically a borane-TMEDA adduct derived from (+)-α-pinene. This compound matters as a critical enantioenriched source of the isopinocampheylborane moiety, enabling highly stereoselective transformations in fine chemical synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for asymmetric synthesis, particularly in the production of chiral alcohols and amines via hydroboration and reduction reactions.

Application

• Asymmetric Hydroboration: Key reagent for the enantioselective hydroboration of prochiral alkenes, a fundamental step in synthesizing chiral alcohols with high optical purity.
• Chiral Auxiliary & Ligand Synthesis: Serves as a precursor for constructing chiral boron-based ligands and auxiliaries used in catalytic asymmetric processes.
• Pharmaceutical Intermediate Production: Enables the stereocontrolled synthesis of complex, biologically active molecules, including active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for activity.
• Academic & Process R&D: Essential tool compound in academic laboratories and industrial R&D for developing new asymmetric methodologies and scaling chiral processes.
• Fine Chemical Manufacturing: Applied in the custom synthesis of high-value, enantiomerically enriched specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	(+)-Isopinocampheylborane Tmeda Complex
CAS No.	68297-74-5
Molecular Formula	C₁₇H₃₃BN₂
Molecular Weight	276.27 g/mol
Synonyms	(+)-Isopinocampheylborane-TMEDA Complex; (1R)-(-)-Isopinocampheylborane-TMEDA Adduct; (1R,2S,5R)-(-)-Isopinocampheylborane-N,N,N',N'-Tetramethylethylenediamine Complex; B-[(1R,2S,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane - TMEDA (1:1); (-)-IpcBH₂•TMEDA; IpcBH₂•TMEDA; (1R)-IpcBH₂•TMEDA; Borane, [(1R,2S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]-, compd. with N,N,N',N'-tetramethylethylenediamine (1:1)
EINECS	Contact for details

Quality Control

Our (+)-Isopinocampheylborane Tmeda Complex is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess. Each lot undergoes rigorous analytical testing, including NMR, chiral HPLC, and titration methods, to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) with full analytical data are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is moisture-sensitive (hygroscopic) and easily oxidized; prolonged exposure to air or moisture must be avoided to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (NMR)	≥ 95%
Enantiomeric Excess (Chiral HPLC)	≥ 98% ee
Assay (Titration)	Contact for details
Solubility	Soluble in common organic solvents (e.g., THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.