Description

Zonisamide is a synthetic sulfonamide derivative and a potent anticonvulsant agent. It is a critical active pharmaceutical ingredient (API) valued for its broad-spectrum efficacy in managing seizure disorders. This compound is essential for pharmaceutical manufacturers developing and producing antiepileptic medications. Zonisamide CAS NO 68291-97-4 is supplied under stringent quality control to meet the exacting standards of the global pharmaceutical industry.

Application

• Primary Pharmaceutical Ingredient: As the active pharmaceutical ingredient (API) in the formulation of antiepileptic drugs for the treatment of partial and generalized seizures.
• Neurological Disorder Treatment: Used in medications for adjunctive therapy in adults with partial-onset seizures.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological research for developing new central nervous system (CNS) therapeutics.
• Generic Drug Manufacturing: A vital component for manufacturers producing generic versions of established zonisamide-based medications.
• Clinical Trial Material: Supplied as a high-purity compound for use in clinical studies and bioequivalence testing.
• Veterinary Medicine: Potential application in veterinary neurology for seizure control in companion animals, subject to regulatory approval.

Basic Information

Item	Detail
Product Name	Zonisamide
CAS No.	68291-97-4
Molecular Formula	C8H8N2O3S
Molecular Weight	212.23 g/mol
Synonyms	1,2-Benzisoxazole-3-methanesulfonamide; AD-810; CI-912; Excegran; Zonegran; 3-(Sulfamoylmethyl)-1,2-benzisoxazole; ZNS
EINECS	Contact for details

Quality Control

Our Zonisamide is manufactured and tested to meet the highest pharmacopeial standards, including USP and EP monographs where applicable. Every batch undergoes comprehensive analytical testing for identity, purity, and impurity profiles using advanced techniques like HPLC and GC. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with cGMP guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.