Description

2-(3,4-Difluorophenyl)Indole is a high-value, multi-functional heterocyclic building block characterized by its indole core substituted with a difluorinated phenyl ring. This molecular architecture makes it a critical intermediate for the synthesis of advanced pharmaceuticals and agrochemicals, where its fluorine atoms are leveraged to modulate biological activity, metabolic stability, and lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the effects of fluorination on molecular properties and reactivity.
• Ligand and Catalyst Development: Utilized in the design of specialized ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	2-(3,4-Difluorophenyl)Indole
CAS No.	68290-36-8
Molecular Formula	C14H9F2N
Molecular Weight	229.23 g/mol
Synonyms	2-(3,4-Difluorophenyl)-1H-indole; 1H-Indole, 2-(3,4-difluorophenyl)-; 3,4-Difluoro-2-indolylbenzene; 2-(3,4-Difluorophenyl)indole; 68290-36-8; 2-(3,4-Difluorophenyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorophenyl)Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for pharmaceutical intermediates (ICH Q7, GMP where applicable) and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.