Description

1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2,5-Dione is a specialized heterocyclic building block featuring a maleimide core substituted with a trifluoromethoxy phenyl group. This compound matters for its unique chemical reactivity and the properties imparted by the trifluoromethoxy moiety, which is valuable in advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve activity and environmental profile.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of high-performance polymers, resins, and coatings with specific thermal or chemical resistance.
• Chemical Biology Probe Development: Utilized for labeling proteins or other biomolecules due to the reactivity of the maleimide group with thiols.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic frameworks and fluorinated compounds.

Basic Information

Product Name	1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2,5-Dione
CAS No.	68255-58-3
Molecular Formula	C11H6F3NO3
Molecular Weight	257.17 g/mol
Synonyms	4-(Trifluoromethoxy)phenylmaleimide; 1-[4-(Trifluoromethoxy)phenyl]-1H-pyrrole-2,5-dione; N-[4-(Trifluoromethoxy)phenyl]maleimide; 2,5-Pyrroledione, 1-[4-(trifluoromethoxy)phenyl]-; Maleimide, N-[4-(trifluoromethoxy)phenyl]-; 68255-58-3; 4-Trifluoromethoxyphenylmaleimide
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2,5-Dione undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.