Description

6-Nitro-3-(Pyrrolidin-1-Yl)-1H-Indazole is a high-purity, functionalized indazole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of targeted kinase inhibitors and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The indazole-pyrrolidine-nitrogen oxide structure makes it a valuable fragment for designing potent and selective kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological processes and identify new therapeutic targets.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and new reaction methodologies.

Basic Information

Product Name	6-Nitro-3-(Pyrrolidin-1-Yl)-1H-Indazole
CAS No.	68159-25-1
Molecular Formula	C11H12N4O2
Molecular Weight	232.24 g/mol
Synonyms	6-Nitro-3-(1-pyrrolidinyl)-1H-indazole; 1H-Indazole, 6-nitro-3-(1-pyrrolidinyl)-; 3-Pyrrolidin-1-yl-6-nitro-1H-indazole; 6-Nitro-3-pyrrolidin-1-yl-1H-indazole; 6-Nitro-3-(pyrrolidin-1-yl)-1H-indazole; 68159-25-1; 6-Nitro-3-(1-pyrrolidinyl)indazole
EINECS	Contact for details

Quality Control

Our 6-Nitro-3-(Pyrrolidin-1-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.