Description

6-Nitro-3-(Piperidin-1-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic indazole core. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies and contract research organizations (CROs) specializing in oncology, neurology, and inflammation require this precise intermediate to accelerate their drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of novel kinase inhibitors, a major class of targeted cancer therapies.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and pre-clinical development.
• Biochemical Tool Compound: Utilized in academic and industrial laboratories as a research chemical to study specific biological mechanisms.
• High-Value Fine Chemical: Employed in the synthesis of other complex, nitro-substituted heterocyclic compounds for specialized applications.

Basic Information

Product Name	6-Nitro-3-(Piperidin-1-Yl)-1H-Indazole
CAS No.	68159-21-7
Molecular Formula	C12H14N4O2
Molecular Weight	246.27 g/mol
Synonyms	6-Nitro-3-(1-piperidinyl)-1H-indazole; 3-(Piperidin-1-yl)-6-nitro-1H-indazole; 1H-Indazole, 6-nitro-3-(1-piperidinyl)-; 6-Nitro-3-piperidin-1-yl-1H-indazole; 6-Nitro-3-(piperidin-1-yl)-1H-indazole; 68159-21-7; 6-Nitro-3-(1-piperidinyl)indazole
EINECS	Contact for details

Quality Control

Our 6-Nitro-3-(Piperidin-1-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality assurance supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.