Description

1,4-Dihydro-1-Phenyl-4-(Trimethylsilyl)-5H-Tetrazol-5-One is a specialized organosilicon heterocyclic compound that serves as a valuable synthetic intermediate. Its unique structure, featuring both a tetrazolone ring and a trimethylsilyl protecting group, makes it a critical reagent in advanced organic synthesis. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing nitrogen-rich heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its tetrazole moiety.
• Organosilicon Chemistry: Serves as a precursor or reagent in reactions exploring silyl group transfer and protection/deprotection strategies.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced materials.
• Academic & Contract Research: Employed in methodological studies and as a standard in synthetic organic chemistry research within universities and CROs.

Basic Information

Product Name	1,4-Dihydro-1-Phenyl-4-(Trimethylsilyl)-5H-Tetrazol-5-One
CAS No.	68140-26-1
Molecular Formula	C11H15N4OSi
Molecular Weight	247.35 g/mol
Synonyms	1-Phenyl-4-(trimethylsilyl)-1,4-dihydro-5H-tetrazol-5-one; 4-(Trimethylsilyl)-1-phenyl-1,4-dihydro-5H-tetrazol-5-one; 1-Phenyl-4-trimethylsilyl-1,4-dihydrotetrazol-5-one; Tetrazolone silyl ether derivative; 5H-Tetrazol-5-one, 1,4-dihydro-1-phenyl-4-(trimethylsilyl)-; TMST; Phenyl-trimethylsilyl-tetrazolone
EINECS	Contact for details

Quality Control

Every batch of our 1,4-Dihydro-1-Phenyl-4-(Trimethylsilyl)-5H-Tetrazol-5-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.