Description

4-Methyl-7-Trimethylsiloxycoumarin is a specialized organosilicon derivative of the coumarin family, serving as a key intermediate in advanced organic synthesis. Its value lies in its functionalized structure, which combines the photophysical properties of a coumarin core with the protective and reactivity-modifying trimethylsilyl (TMS) group. This compound is primarily needed by research and development chemists, as well as manufacturers in the fine chemical, pharmaceutical, and advanced material sectors for constructing complex molecules, developing fluorescent probes, and creating functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs) requiring coumarin-based scaffolds.
• Fluorescent Probe Synthesis: Acts as a precursor for developing sensitive fluorescent dyes and sensors used in bioimaging and analytical chemistry.
• Polymer & Material Science: Incorporated into specialty polymers and advanced materials to impart specific optical or surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and as a protected form of 7-hydroxycoumarin derivatives for selective functionalization.
• Photoresist & Electronic Chemicals: Explored in the formulation of advanced photoresists and electronic materials for the semiconductor industry.
• Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new chemical reactions and properties.

Basic Information

Product Name	4-Methyl-7-Trimethylsiloxycoumarin
CAS No.	67909-31-3
Molecular Formula	C₁₅H₂₀O₃Si
Molecular Weight	276.41 g/mol
Synonyms	7-(Trimethylsiloxy)-4-methylcoumarin; 4-Methyl-7-(trimethylsilyloxy)-2H-chromen-2-one; 4-Methylumbelliferone trimethylsilyl ether; 4-MU TMS ether; 7-Hydroxy-4-methylcoumarin trimethylsilyl ether; 7-Trimethylsilyloxy-4-methylcoumarin; TMS-4-MU; 4-Methyl-7-O-trimethylsilylcoumarin
EINECS	Contact for details

Quality Control

Our 4-Methyl-7-Trimethylsiloxycoumarin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.