Description

1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperazine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a piperazine ring with a substituted 1,2,4-thiadiazole moiety, which is crucial for imparting specific biological and physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and antimicrobial applications.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial labs for constructing complex nitrogen- and sulfur-containing heterocycles.
• Ligand and Catalyst Development: The piperazine nitrogen atoms can act as coordination sites in the development of novel ligands for catalytic or metal-chelating applications.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or organic electronic materials requiring specific heterocyclic units.

Basic Information

Product Name	1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperazine
CAS No.	67869-94-7
Molecular Formula	C7H12N4S
Molecular Weight	184.26 g/mol
Synonyms	5-Piperazin-1-yl-3-methyl-1,2,4-thiadiazole; 3-Methyl-5-(piperazin-1-yl)-1,2,4-thiadiazole; 1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperazine; 67869-94-7; 3-Methyl-5-piperazinyl-1,2,4-thiadiazole; Piperazine, 1-(3-methyl-1,2,4-thiadiazol-5-yl)-; 5-(1-Piperazinyl)-3-methyl-1,2,4-thiadiazole
EINECS	Contact for details

Quality Control

Our 1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.