Description

Dl-Methionine-2-D1 CAS NO 67866-74-4 is a deuterium-labeled isotopologue of the essential amino acid DL-Methionine, where a hydrogen atom at the 2-position is replaced by deuterium. This stable isotope-labeled compound is a critical tool in advanced research and analytical chemistry, enabling precise metabolic and pharmacokinetic studies. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for applications such as mass spectrometry-based quantification, tracer studies, and the development of novel diagnostic agents.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis of methionine and related metabolites in biological samples.
• Metabolic Pathway Tracer: Enables the detailed study of methionine metabolism, transmethylation, and transsulfuration pathways in vivo and in vitro.
• Pharmaceutical Research & Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for new drug candidates targeting amino acid pathways.
• Biochemical Research: Serves as a probe in protein and peptide studies to investigate structure, function, and turnover rates.
• Nutritional Science: Applied in advanced studies to understand the bioavailability and utilization of methionine in animal and human nutrition.
• Diagnostic Agent Development: A potential precursor in the synthesis of labeled compounds for clinical diagnostics and imaging.

Basic Information

Product Name	Dl-Methionine-2-D1
CAS No.	67866-74-4
Molecular Formula	C5H10DNO2S
Molecular Weight	150.22 g/mol (approx.)
Synonyms	(±)-2-Amino-4-(methylthio)butyric acid-2-d1; DL-Methionine-2-d; DL-Methionine-2-d1; Methionine-d1 (2-position); 2-Deuterio-DL-methionine; (RS)-2-Amino-4-(methylsulfanyl)butanoic-2-d acid; 2H-DL-Methionine; Deuterated DL-Methionine
EINECS	Contact for details

Quality Control

Our Dl-Methionine-2-D1 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is analyzed using advanced techniques including NMR and Mass Spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and purity is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.