Description

3-Formylthiophene-2-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both an aldehyde and an ester group on a thiophene scaffold, enabling its use in the construction of complex molecular architectures. It is primarily sought after by research and development laboratories and industrial chemists in the pharmaceutical, agrochemical, and material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene moiety for bioactivity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Chemistry: Acts as a building block for synthesizing novel heterocyclic dyes and functional colorants.
• Academic and Contract Research: A critical reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	3-Formylthiophene-2-Carboxylic Acid Methyl Ester
CAS No.	67808-71-3
Molecular Formula	C7H6O3S
Molecular Weight	170.19 g/mol
Synonyms	Methyl 3-formylthiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-formyl-, methyl ester; Methyl 3-formyl-2-thiophenecarboxylate; 3-Formyl-2-thiophenecarboxylic acid methyl ester; 2-(Methoxycarbonyl)thiophene-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Formylthiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.