Description

Methyl 5-Cyanothiophene-2-Carboxylate is a high-value heterocyclic building block featuring both cyano and ester functional groups on a thiophene core. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a versatile intermediate. It is primarily sought after by research and development chemists and process scale-up teams in fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small molecule drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require a thiophene-based structural motif.
• Material Science Precursor: Serves as a monomer or starting material for the synthesis of conjugated polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-catalyzed reactions and organocatalysts.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and functional pigments.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services in fine chemical production.

Basic Information

Product Name	Methyl 5-Cyanothiophene-2-Carboxylate
CAS No.	67808-34-8
Molecular Formula	C7H5NO2S
Molecular Weight	167.19 g/mol
Synonyms	5-Cyanothiophene-2-carboxylic acid methyl ester; Methyl 5-cyanothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-cyano-, methyl ester; Methyl 5-cyano-2-thiophenecarboxylate; 5-Cyano-2-thiophenecarboxylic acid methyl ester; 2-Methoxycarbonyl-5-cyanothiophene; 5-CN-Thiophene-2-COOMe
EINECS	Contact for details

Quality Control

Our Methyl 5-Cyanothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.