Description

Methyl 4-Cyanothiophene-2-Carboxylate is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its bifunctional structure, featuring both a nitrile and an ester group on a thiophene core, enabling diverse chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Chemical Research & Development: Used extensively in academic and industrial labs for methodological studies and exploring new heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Methyl 4-Cyanothiophene-2-Carboxylate
CAS No.	67808-33-7
Molecular Formula	C7H5NO2S
Molecular Weight	167.19 g/mol
Synonyms	Methyl 4-cyanothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-cyano-, methyl ester; 4-Cyanothiophene-2-carboxylic acid methyl ester; Methyl 4-cyano-2-thiophenecarboxylate; 2-Methoxycarbonyl-4-cyanothiophene; 4-Cyano-2-methoxycarbonylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 4-Cyanothiophene-2-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.