Description

Bis(2,2,2-Trifluoroethoxy)Triphenylphosphorane is a specialized organophosphorus reagent featuring trifluoroethoxy substituents, which significantly enhance its reactivity and stability profile. This compound is valued for its role as a potent fluorinating and alkoxylating agent in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules and introducing fluorine-containing functional groups.

Application

• As a key reagent in the synthesis of fluorinated pharmaceuticals and active pharmaceutical ingredients (APIs).
• For the preparation of fluorinated agrochemical intermediates, such as herbicides and pesticides.
• In nucleophilic fluorination reactions to replace hydroxyl or other leaving groups with fluorine atoms.
• As a precursor or catalyst in the synthesis of specialty polymers and advanced materials with unique surface properties.
• For alkoxylation reactions in fine chemical and complex molecule synthesis.
• In academic and industrial R&D for developing new synthetic methodologies involving phosphorus chemistry.

Basic Information

Product Name	Bis(2,2,2-Trifluoroethoxy)Triphenylphosphorane
CAS No.	67696-25-7
Molecular Formula	C22H19F6O2P
Molecular Weight	460.35 g/mol
Synonyms	Triphenylbis(2,2,2-trifluoroethoxy)phosphorane; Bis(2,2,2-trifluoroethoxy)(triphenyl)phosphorane; Phosphorane, bis(2,2,2-trifluoroethoxy)triphenyl-; (2,2,2-Trifluoroethoxy)triphenylphosphorane (ambiguous); TPBTFP; Trifluoroethoxy Triphenylphosphorane
EINECS	Contact for details

Quality Control

Our Bis(2,2,2-Trifluoroethoxy)Triphenylphosphorane is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms
31P NMR	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.