Description

S-Nitrosomercaptoethanol is a specialized organosulfur compound featuring both nitrosyl and thiol functional groups. This unique structure makes it a valuable reagent for introducing S-nitrosothiol (SNO) motifs, which are critical in the study of nitric oxide (NO) signaling and protein S-nitrosylation. It is essential for researchers and manufacturers in life sciences and pharmaceutical development who require precise tools for redox biology and post-translational modification studies. The compound, identified as CAS NO 67616-44-8, is a key building block for biochemical research and advanced material synthesis.

Application

• Biochemical Research: As a precursor for synthesizing S-nitrosothiols (RSNOs) to study nitric oxide donor chemistry and signaling pathways.
• Pharmaceutical Intermediates: Used in the development of novel therapeutics targeting cardiovascular diseases and conditions involving NO metabolism.
• Proteomics & Protein Labeling: Employed for the selective S-nitrosylation of cysteine residues in proteins to investigate structure-function relationships.
• Polymer & Material Science: Acts as a modifying agent or cross-linker in the synthesis of functional polymers with specific redox-responsive properties.
• Analytical Standards: Serves as a reference standard in chromatography (HPLC, LC-MS) for quantifying S-nitrosylated compounds in complex matrices.
• Cell Signaling Studies: Utilized in cell culture and in vitro assays to modulate intracellular NO levels and study downstream effects.

Basic Information

Product Name	S-Nitrosomercaptoethanol
CAS No.	67616-44-8
Molecular Formula	C₂H₅NO₂S
Molecular Weight	107.13 g/mol
Synonyms	2-Hydroxyethyl nitrososulfenate; 2-Mercaptoethanol S-nitrosyl derivative; S-Nitroso-2-mercaptoethanol; SNO-ME; Nitrosyl mercaptoethanol; Thionitrous acid S-(2-hydroxyethyl) ester; NO donor reagent
EINECS	Contact for details

Quality Control

Our S-Nitrosomercaptoethanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including purity assay by HPLC, identity confirmation via FT-IR and NMR spectroscopy, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at recommended cold temperatures (e.g., -20°C or below) to minimize decomposition and oxidation. Keep the container in a dry, well-ventilated area separate from incompatible materials.

Specification

Item	Specification
Appearance	Pale yellow to orange liquid / solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.