Description

(R)-1,2,3,4,5,6,7,8-Octahydro-1-[(4-Methoxyphenyl)Methyl]-2-Methylisoquinoline is a chiral, non-natural isoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block and intermediate for creating complex molecules with specific stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Catalyst Ligand Synthesis: Used to develop novel chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Research: Acts as a building block for creating novel, stereospecific pesticides and herbicides.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways in organic chemistry.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, complex molecules for various industrial research applications.

Basic Information

Product Name	(R)-1,2,3,4,5,6,7,8-Octahydro-1-[(4-Methoxyphenyl)Methyl]-2-Methylisoquinoline
CAS No.	67596-84-3
Molecular Formula	C18H25NO
Molecular Weight	271.40 g/mol
Synonyms	(R)-1,2,3,4,5,6,7,8-Octahydro-1-(4-methoxybenzyl)-2-methylisoquinoline; (R)-1-(4-Methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline; (R)-1-[(4-Methoxyphenyl)methyl]-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline; (R)-PMQ; (R)-enantiomer of Octahydro-1-(4-methoxybenzyl)-2-methylisoquinoline; (R)-1,2,3,4,5,6,7,8-Octahydro-1-(p-methoxybenzyl)-2-methylisoquinoline; (R)-1-(p-Methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (R)-1,2,3,4,5,6,7,8-Octahydro-1-[(4-Methoxyphenyl)Methyl]-2-Methylisoquinoline is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high purity and stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.