Description

(R)-3,4-Dihydro-8-Methoxy-3,7-Dimethyl-1H-2-Benzopyran-1-One is a chiral, non-racemic organic compound belonging to the benzopyran class. This specific enantiomer is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries. The compound's defined stereochemistry and functional groups make it crucial for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialty chemicals, fragrances, and advanced materials where specific chirality is required.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(R)-3,4-Dihydro-8-Methoxy-3,7-Dimethyl-1H-2-Benzopyran-1-One
CAS No.	67549-57-9
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	(R)-8-Methoxy-3,7-dimethyl-3,4-dihydro-1H-isochromen-1-one; (R)-8-Methoxy-3,7-dimethylchroman-1-one; (R)-3,4-Dihydro-8-methoxy-3,7-dimethyl-1H-2-benzopyran-1-one; (R)-Dihydrokavain; (R)-DHK; (R)-5,6-Dehydrokavain; (R)-Desmethoxyyangonin; (R)-3,7-Dimethyl-8-methoxychroman-1-one
EINECS	Contact for details

Quality Control

Our (R)-3,4-Dihydro-8-Methoxy-3,7-Dimethyl-1H-2-Benzopyran-1-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.