Description

(E)-1-Chloro-3-Bromo-1-Propene is a high-purity halogenated alkene building block of significant importance in advanced organic synthesis. Its value lies in its bifunctional reactivity, serving as a versatile electrophilic synthon for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Heck, Suzuki, and Negishi couplings for carbon-carbon bond formation.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the development of specialty polymers and resins.
• Material Science Research: Utilized in the creation of novel organic materials and liquid crystals due to its specific stereochemistry and reactivity.
• Chemical Derivatization: Employed for introducing chloro- and bromo- functional groups into target molecules in a controlled, stepwise manner.

Basic Information

Product Name	(E)-1-Chloro-3-Bromo-1-Propene
CAS No.	67546-50-3
Molecular Formula	C3H4BrCl
Molecular Weight	155.42 g/mol
Synonyms	trans-1-Chloro-3-bromopropene; (E)-3-Bromo-1-chloropropene; 1-Chloro-3-bromo-1-propene (E)-; 1-Propene, 1-chloro-3-bromo-, (E)-; 3-Bromo-1-chloro-1-propene; (E)-3-Bromoallyl chloride; trans-3-Bromoallyl chloride
EINECS	Contact for details

Quality Control

Our (E)-1-Chloro-3-Bromo-1-Propene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture ingress and volatility.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
(E)-Isomer Content (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.