Description

(Z)-1-Bromo-3-Chloro-1-Propene is a halogenated alkene building block of significant interest in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering distinct handles for sequential cross-coupling and substitution reactions to construct complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in constructing chiral centers and heterocyclic systems.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its reactivity to introduce halogenated propene motifs.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique halogenated properties.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) and nucleophilic substitutions to create complex organic molecules.
• Ligand and Catalyst Preparation: Utilized for the synthesis of specialized phosphine or nitrogen-based ligands for asymmetric catalysis.
• Flavor & Fragrance Industry: May be used as an intermediate for synthesizing specific aroma chemicals, though strict purity controls are essential.

Basic Information

Product Name	(Z)-1-Bromo-3-Chloro-1-Propene
CAS No.	67546-49-0
Molecular Formula	C3H4BrCl
Molecular Weight	155.42 g/mol
Synonyms	1-Bromo-3-chloro-1-propene (Z-isomer); (Z)-3-Chloro-1-bromopropene; (Z)-3-Chloroallyl bromide; trans-1-Bromo-3-chloropropene; (Z)-1-Bromo-3-chloroprop-1-ene; 67546-49-0; (Z)-β-Bromochloropropene
EINECS	Contact for details

Quality Control

Our (Z)-1-Bromo-3-Chloro-1-Propene is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. Ensure containers are kept upright and securely sealed to prevent moisture ingress and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.