Description

1H-Indole-5,6-Dione,2,3-Dihydro-3-Hydroxy-1-(1-Methylethyl)-,(R)-(9Ci) is a high-purity, chiral indole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for the development of novel pharmaceuticals and bioactive molecules, offering a unique stereochemical handle for creating targeted compounds. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for use in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Serves as a building block for novel active ingredients in crop protection products.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its quinone and hydroxyl functional groups.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty chemicals.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands for catalytic asymmetric transformations.

Basic Information

Product Name	1H-Indole-5,6-Dione,2,3-Dihydro-3-Hydroxy-1-(1-Methylethyl)-,(R)-(9Ci)
CAS No.	67491-46-7
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	(R)-3-Hydroxy-1-isopropylindole-5,6-dione; 2,3-Dihydro-3-hydroxy-1-(1-methylethyl)-1H-indole-5,6-dione, (R)-; 1H-Indole-5,6-dione, 2,3-dihydro-3-hydroxy-1-(1-methylethyl)-, (R)-; (R)-1-Isopropyl-3-hydroxyindole-5,6-dione; (R)-3-Hydroxy-1-isopropyl-2,3-dihydro-1H-indole-5,6-dione; 5,6-Dihydroxyindole derivative (R)-isomer
EINECS	Contact for details

Quality Control

Our 1H-Indole-5,6-Dione derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.