Description

1H-Benzimidazole-2-Acetonitrile,α-Methyl-(9Ci) is a high-purity, versatile benzimidazole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring fine chemical synthesis, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production, need this high-quality intermediate for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel benzimidazole-based active pharmaceutical ingredients (APIs), including potential antivirals, antifungals, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as fungicides and herbicides, leveraging the benzimidazole scaffold's bioactivity.
• Material Science Research: Serves as a building block for creating functional organic materials, including ligands for catalysis, organic semiconductors, and metal-organic frameworks (MOFs).
• Dye & Pigment Industry: Acts as an intermediate in the manufacture of specialized dyes and pigments, where the benzimidazole core contributes to color fastness and stability.
• Biochemical Research: Utilized as a standard or reagent in biochemical assays and proteomics research to study enzyme inhibition and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs) developing proprietary compounds.

Basic Information

Product Name	1H-Benzimidazole-2-Acetonitrile,α-Methyl-(9Ci)
CAS No.	67431-21-4
Molecular Formula	C11H9N3
Molecular Weight	183.21 g/mol
Synonyms	2-(1H-Benzimidazol-2-yl)propanenitrile; α-Methyl-1H-benzimidazole-2-acetonitrile; 2-(1H-Benzo[d]imidazol-2-yl)propanenitrile; 1H-Benzimidazole-2-acetonitrile, α-methyl-; 2-(1H-Benzimidazol-2-yl)-2-methylacetonitrile; 2-Cyano-1-(1H-benzimidazol-2-yl)-1-ethanone (tautomer); Benzimidazole propanenitrile derivative; 67431-21-4
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-2-Acetonitrile,α-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.