Description

(1β,6β)-2β-(Benzyloxy)-3,7-Dioxabicyclo[4.1.0]Heptane-5α-Ol is a specialized bicyclic ether derivative with a benzyl-protected hydroxyl group, serving as a valuable chiral building block and synthetic intermediate. Its unique oxabicyclo[4.1.0]heptane scaffold is of significant interest for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for advanced organic synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Asymmetric Synthesis: Employed as a stereodefined building block in catalytic asymmetric reactions to introduce complex ring systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for probing new biological targets.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D: A valuable tool for methodological development in organic synthesis and total synthesis of natural products.

Basic Information

Product Name	(1β,6β)-2β-(Benzyloxy)-3,7-Dioxabicyclo[4.1.0]Heptane-5α-Ol
CAS No.	67412-71-9
Molecular Formula	C₁₃H₁₆O₄
Molecular Weight	236.26 g/mol
Synonyms	2-Benzyloxy-3,7-dioxabicyclo[4.1.0]heptan-5-ol; 5-Hydroxy-2-(phenylmethoxy)-3,7-dioxabicyclo[4.1.0]heptane; (1R,2R,5S,6R)-2-(Benzyloxy)-3,7-dioxabicyclo[4.1.0]heptan-5-ol; (1β,6β)-2β-(Benzyloxy)-3,7-dioxabicyclo[4.1.0]heptane-5α-ol; Benzyl 2,3-anhydro-5-deoxy-β-D-ribofuranoside (related structure); Oxabicycloheptanol derivative
EINECS	Contact for details

Quality Control

Our (1β,6β)-2β-(Benzyloxy)-3,7-Dioxabicyclo[4.1.0]Heptane-5α-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible results for your critical synthetic steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.