Description

Formamide, n-[2-Hydroxy-5-[1-Hydroxy-2-[[2-(4-Methoxyphenyl)-1-Methylethyl]Amino]Ethyl]Phenyl]-, [R-(R*,S*)]- is a specialized chiral organic compound with a complex molecular structure featuring formamide, phenolic, and amino alcohol functional groups. This compound is valued for its role as a high-purity pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly those targeting adrenergic receptors.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel therapeutic agents.
• Asymmetric Synthesis: Serves as a precursor or chiral auxiliary in stereoselective chemical reactions.
• Biochemical Research: Employed in studies involving receptor binding and signal transduction pathways.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	Formamide, n-[2-Hydroxy-5-[1-Hydroxy-2-[[2-(4-Methoxyphenyl)-1-Methylethyl]Amino]Ethyl]Phenyl]-, [R-(R*,S*)]-
CAS No.	67346-51-4
Molecular Formula	C20H26N2O4
Molecular Weight	358.43 g/mol
Synonyms	N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1S)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide; (R,S)-Formoterol Impurity; Formoterol Related Compound; 5-[(1R)-1-Hydroxy-2-[[(1S)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2-formamidophenol; Arformoterol Intermediate; Oxeze Impurity; Foradil Related Substance
EINECS	Contact for details

Quality Control

This high-purity intermediate is produced under controlled conditions with stringent quality protocols. Every batch is analyzed to ensure identity, purity, and stereochemical integrity, typically meeting standards suitable for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment to support regulatory filings and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.