Description

2-[(tert-Butoxycarbonyl)Amino]-3-(5-Bromo-1H-Indol-3-Yl)Propanoic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block for the development of novel bioactive molecules, particularly in peptide and peptidomimetic chemistry. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex indole-based compounds and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Peptide Synthesis: Used as a Boc-protected tryptophan analog for the solid-phase and solution-phase synthesis of modified peptides with enhanced stability or biological activity.
• Chemical Biology Research: Employed in the design and construction of molecular probes and labeled compounds for studying protein-protein interactions and enzyme mechanisms.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of focused libraries for high-throughput screening.
• API Development: Integral in the research and development stages of new Active Pharmaceutical Ingredients (APIs), especially those containing halogenated indole moieties.

Basic Information

Product Name	2-[(tert-Butoxycarbonyl)Amino]-3-(5-Bromo-1H-Indol-3-Yl)Propanoic Acid
CAS No.	67308-26-3
Molecular Formula	C₁₆H₁₉BrN₂O₄
Molecular Weight	383.24 g/mol
Synonyms	Boc-5-Bromo-DL-tryptophan; 5-Bromo-N-(tert-butoxycarbonyl)-DL-tryptophan; Boc-5-Br-Trp-OH; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(5-bromo-1H-indol-3-yl)propanoic acid; N-Boc-5-bromotryptophan; 2-(Boc-amino)-3-(5-bromo-1H-indol-3-yl)propanoic acid; 5-Bromo-N-Boc-tryptophan; DL-5-Bromotryptophan, N-Boc-protected
EINECS	Contact for details

Quality Control

Our 2-[(tert-Butoxycarbonyl)Amino]-3-(5-Bromo-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.