Description

Morphine-D3 CAS NO 67293-88-3 is a stable isotope-labeled analog of morphine, where three hydrogen atoms are replaced by deuterium. This compound is essential as a high-purity internal standard for the accurate quantification of morphine in complex biological matrices using advanced analytical techniques. It is a critical tool for pharmaceutical research, forensic toxicology, and clinical laboratories requiring precise and reliable analytical results.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application as a deuterated internal standard for the sensitive and specific quantification of morphine in pharmacokinetic and bioanalytical studies.
• Pharmaceutical R&D and Metabolism Studies: Used to trace drug metabolism, study metabolic pathways, and understand the pharmacokinetic profile of morphine and related opioids.
• Forensic and Clinical Toxicology: Enables accurate measurement of morphine concentrations in blood, urine, and other specimens for medico-legal cases, overdose analysis, and therapeutic drug monitoring.
• Reference Standard for Quality Control: Serves as a certified reference material (CRM) for calibrating instruments and validating analytical methods in pharmaceutical quality control laboratories.
• Doping Control in Sports: Employed in anti-doping laboratories to reliably detect and confirm the presence of morphine, a prohibited substance in athletic competitions.
• Academic and Biomedical Research: Facilitates research into opioid receptor interactions, pain management mechanisms, and the development of novel analgesic agents.

Basic Information

Product Name	Morphine-D3
CAS No.	67293-88-3
Molecular Formula	C₁₇H₁₆D₃NO₃
Molecular Weight	288.36 g/mol
Synonyms	(5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol-d3; Morphine-d3 (N-methyl-d3); (-)-Morphine-d3; 17-Methylmorphine-d3; Deuterated Morphine; Morphine Internal Standard; Morphine-D3 Hydrochloride (salt form); Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5α,6α)-, d3-
EINECS	Contact for details

Quality Control

Our Morphine-D3 is manufactured under strict quality management systems to ensure the highest standards of purity and isotopic enrichment, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic purity (deuterium incorporation), and chemical identity. We adhere to relevant guidelines for the production of reference standards and can provide materials suitable for use in GLP/GMP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.