Description

H-Dl-Tic-Oh CAS NO 67123-97-1 is a non-proteinogenic amino acid derivative, specifically a synthetic analog of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic). This compound is a critical chiral building block and intermediate in advanced pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of peptidomimetics and protease inhibitors.
• Medicinal Chemistry Research: Building block for creating novel drug candidates with potential activity in central nervous system (CNS) disorders.
• Peptide Synthesis: Used in the preparation of constrained peptides to improve metabolic stability and bioavailability.
• Biochemical Research: Serves as a tool compound in enzyme inhibition studies and receptor binding assays.
• Process Chemistry: Intermediate in the scalable synthesis of active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	H-Dl-Tic-Oh
CAS No.	67123-97-1
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, DL-Tic-OH; (±)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; DL-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; H-DL-Tic-OH; rac-Tic-OH; Tic acid; 3-Carboxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our H-Dl-Tic-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.