Description

Aristolochic Acid is a naturally occurring nitrophenanthrene carboxylic acid, primarily sourced from plants of the *Aristolochia* genus. Its unique chemical structure makes it a critical reference standard and research compound for toxicological and pharmacological studies. This product is essential for laboratories and research institutions focused on studying nephrotoxicity, carcinogenicity, and the mechanisms of DNA adduct formation.

Application

• Pharmaceutical Research: Used as a key analytical reference standard in studies investigating drug-induced toxicities and carcinogenic pathways.
• Toxicology & Safety Assessment: Serves as a model compound for evaluating the safety profiles of herbal medicines and natural products.
• Biochemical Research: Employed in mechanistic studies to understand its interaction with DNA and proteins, leading to adduct formation.
• Quality Control Laboratories: Acts as a certified reference material (CRM) for the identification and quantification of aristolochic acids in complex matrices.
• Academic Research: Utilized in universities and institutes for fundamental research in chemical biology and molecular toxicology.
• Regulatory Compliance Testing: Applied in methods development and validation for monitoring banned substances in traditional medicines and supplements.

Basic Information

Product Name	Aristolochic Acid
CAS No.	67123-64-2
Molecular Formula	C17H11NO7
Molecular Weight	341.27 g/mol
Synonyms	Aristolochic Acid I; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid; Aristolochic Acid A; Tardolyt; Isoaristolochic acid; 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic Acid; ASC; AA-I
EINECS	Contact for details

Quality Control

Our Aristolochic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.