Description

Diethyl Malonate-2-13C is a stable isotope-labeled analog of diethyl malonate, where the carbon atom at the 2-position is the carbon-13 isotope. This compound is an essential building block for the synthesis of complex molecules where isotopic labeling is required for research and analytical purposes. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in metabolic studies, tracer analysis, and the development of labeled active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of carbon-13 labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolic Pathway Analysis: Used as a tracer compound in biomedical and biochemical research to elucidate metabolic pathways and mechanisms.
• Analytical Chemistry Standards: Serves as a high-purity internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• Agrochemical Development: Employed in the synthesis of isotopically labeled pesticides or herbicides for environmental fate and residue analysis studies.
• Fine Chemical Synthesis: A versatile reagent for preparing other carbon-13 labeled fine chemicals, flavors, and fragrances through malonic ester synthesis.
• Material Science Research: Used in the development of novel labeled polymers or organic electronic materials for structural analysis.

Basic Information

Product Name	Diethyl Malonate-2-13C
CAS No.	67035-94-3
Molecular Formula	C13C7H12O4 or C7H12O4 (with 13C at position 2)
Molecular Weight	161.16 g/mol (for 13C labeled form)
Synonyms	Diethyl Malonate-2-13C; Diethyl Propanedioate-2-13C; Malonic Acid Diethyl Ester-2-13C; Diethyl 13C-Malonate; Ethyl Malonate-2-13C; DEM-2-13C; 1,3-Diethyl Propanedioate-2-13C; Carbon-13 Labeled Diethyl Malonate
EINECS	Contact for details

Quality Control

Our Diethyl Malonate-2-13C is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) are provided, detailing parameters such as assay (by GC or HPLC), isotopic purity (by NMR or MS), and specific impurity profiles. We adhere to relevant industry standards for research chemicals, and custom purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment (Position 2)	≥ 99%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.