Description

Cyclopropane, 1,1-Dibromo-2-(Chloromethyl)- is a highly functionalized cyclopropane derivative, serving as a versatile and reactive synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both bromine and chloromethyl substituents, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those containing cyclopropane rings for bioactivity modulation.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific modes of action.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: Serves as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) due to its bromine substituents.
• Ring-Opening & Functionalization: Substrate for studying strain-driven ring-opening reactions and subsequent functionalization to create linear or new cyclic compounds.
• Ligand & Catalyst Development: Intermediate in the preparation of novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Cyclopropane, 1,1-Dibromo-2-(Chloromethyl)-
CAS No.	67003-20-7
Molecular Formula	C4H5Br2Cl
Molecular Weight	248.34 g/mol
Synonyms	1,1-Dibromo-2-(chloromethyl)cyclopropane; 2-(Chloromethyl)-1,1-dibromocyclopropane; (Chloromethyl)-1,1-dibromocyclopropane; 1,1-Dibromo-2-chloromethylcyclopropane; Cyclopropane, 1,1-dibromo-2-(chloromethyl)-; NSC 169102
EINECS	Contact for details

Quality Control

Our Cyclopropane, 1,1-Dibromo-2-(Chloromethyl)- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive halogen substituents, it should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.