Description

Ethyl Pyruvate (3,3,3-D3) is a deuterated isotopologue of the common ester ethyl pyruvate, where three hydrogen atoms on the terminal methyl group are replaced with deuterium. This stable isotope-labeled compound is critical for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, tracer, or building block in the synthesis of labeled compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for quantitative analysis in LC-MS and GC-MS, providing high accuracy in pharmacokinetic and metabolomic studies.
• Metabolic Pathway Tracer: Used in biomedical and biochemical research to elucidate metabolic fluxes and mechanisms in cellular systems.
• Deuterated Pharmaceutical Intermediate: Serves as a key building block in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) for improved drug metabolism and pharmacokinetics (DMPK) studies.
• NMR Spectroscopy Solvent & Reagent: Employed as a solvent or reagent in nuclear magnetic resonance (NMR) spectroscopy due to its deuterium content, reducing interference in proton NMR spectra.
• Agrochemical Research: Used in the development and analysis of deuterated pesticides or herbicides to study environmental fate and degradation pathways.
• Chemical Reference Standard: Provides a certified reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Ethyl Pyruvate (3,3,3-D3)
CAS No.	66966-38-9
Molecular Formula	C5H5D3O3
Molecular Weight	119.13 g/mol (approx.)
Synonyms	Ethyl Pyruvate-d3; Ethyl 2-Oxopropanoate-d3; Pyruvic Acid Ethyl Ester-d3; 3,3,3-Trideuteroethyl Pyruvate; Ethyl 2-Oxopropionate-d3; Ethyl α-Ketopropionate-d3; Deuterated Ethyl Pyruvate; [2H3]-Ethyl Pyruvate
EINECS	Contact for details

Quality Control

Our Ethyl Pyruvate (3,3,3-D3) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, MS, and HPLC, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profiles are provided and available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert gas atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.