Description

1-Bromo-3-(Prop-1-Ynyl)Benzene is a specialized aromatic building block featuring both a bromine substituent and a terminal alkyne group. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in cross-coupling reactions and click chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its reactivity to create diverse heterocyclic structures.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalizing agent for creating conjugated polymers, dendrimers, and advanced materials with tailored electronic or optical properties.
• Chemical Research & Development: A versatile reagent for constructing molecular scaffolds in medicinal chemistry and for use in Huisgen 1,3-dipolar cycloaddition (click chemistry) to create triazole linkages.
• Liquid Crystal & OLED Materials: Employed in the synthesis of organic semiconductors and emissive layers for display and lighting technologies due to its rigid, planar structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical producers for bespoke synthesis projects requiring high-purity, functionalized aromatic compounds.

Basic Information

Product Name	1-Bromo-3-(Prop-1-Ynyl)Benzene
CAS No.	66952-36-1
Molecular Formula	C9H7Br
Molecular Weight	195.06 g/mol
Synonyms	3-Bromophenylacetylene; 1-Bromo-3-ethynylbenzene; 3-Ethynylbromobenzene; m-Bromophenylacetylene; (3-Bromophenyl)acetylene; 3-Bromoethynylbenzene; 3-Bromobenzeneacetylene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Prop-1-Ynyl)Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.