Description

1H-Indole,3-Fluoro-2-Methyl-(9Ci) is a high-purity fluorinated indole derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists working on novel active ingredients, where its specific substitution pattern enables precise structural modifications. The CAS number for this compound is 66946-82-5.

Application

This fluorinated indole derivative serves as a critical synthetic intermediate across several high-value industries.

• Pharmaceutical Intermediates: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Employed in the research and synthesis of advanced organic electronic materials and functional dyes.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and fluorination reactions.
• Chemical Biology: Utilized as a probe or building block for creating labeled compounds and biochemical tools.

Basic Information

Product Name	1H-Indole,3-Fluoro-2-Methyl-(9Ci)
CAS No.	66946-82-5
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	3-Fluoro-2-methyl-1H-indole; 2-Methyl-3-fluoroindole; 3-Fluoro-2-methylindole; 1H-Indole, 3-fluoro-2-methyl-; 66946-82-5; 3-Fluoro-2-methyl-1H-indole (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Indole,3-Fluoro-2-Methyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and traceable material for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.