Description

3-Fluoroindole is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for introducing the indole scaffold with a fluorine atom, enabling the development of novel compounds with modified electronic and steric properties. Pharmaceutical, agrochemical, and material science researchers need it for creating new active ingredients, ligands, and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop novel pesticides and herbicides where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers requiring specific electronic characteristics.
• Chemical Biology & Proteomics: Employed as a probe or labeling reagent to study protein interactions and enzyme mechanisms.
• Academic & Contract Research: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fluorine Chemistry: Acts as a model substrate for studying electrophilic aromatic substitution and other fluorination-related chemical transformations.

Basic Information

Product Name	3-Fluoroindole
CAS No.	66946-81-4
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	1H-Indole, 3-fluoro-; 3-Fluoro-1H-indole; 3-FI; 3-Fluorindole; 3-Fluor-1H-indol; 3-Fluoroindol; 3-Fluoroinodole; 66946-81-4
EINECS	Contact for details

Quality Control

Our 3-Fluoroindole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.