Description

7-Chloro-2-Phenyl-1H-Indole is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and phenyl-substituted structure makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological and physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex, multi-substituted indole libraries for screening.
• Dye & Pigment Industry: Utilized as a starting material for synthesizing specialized indole-based dyes and colorants.

Basic Information

Product Name	7-Chloro-2-Phenyl-1H-Indole
CAS No.	66866-01-1
Molecular Formula	C14H10ClN
Molecular Weight	227.69 g/mol
Synonyms	7-Chloro-2-phenylindole; 2-Phenyl-7-chloro-1H-indole; 1H-Indole, 7-chloro-2-phenyl-; 7-Chloro-2-phenyl-1H-indole; 66866-01-1; 7-Chloro-2-phenylindole; 2-(7-Chlorophenyl)indole (incorrect but common search variant).
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-Phenyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.