Description

Esculin is a naturally occurring coumarin glycoside, a key chemical standard and intermediate in pharmaceutical and biochemical research. Its primary value lies in its role as a reference compound for analytical methods and as a precursor in the synthesis of more complex bioactive molecules. This product is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and diagnostic reagent sectors requiring high-purity biochemical building blocks.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and assay development in drug manufacturing.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly those involving β-glucosidase activity.
• Diagnostic Reagents: Employed in the formulation of culture media and diagnostic kits for microbiological identification.
• Natural Product Isolation & Analysis: Acts as a marker compound for the standardization and authentication of herbal extracts, such as those from horse chestnut or willow bark.
• Cosmeceutical Ingredients: Investigated for its potential skin-brightening and antioxidant properties in advanced cosmetic formulations.
• Academic & Industrial R&D: Utilized as a starting material or intermediate in the synthetic chemistry of novel coumarin derivatives.

Basic Information

Product Name	Esculin
CAS No.	66778-17-4
Molecular Formula	C15H16O9
Molecular Weight	340.28 g/mol
Synonyms	Esculoside; Aesculin; 6,7-Dihydroxycoumarin-6-glucoside; 6-Glucosyl-7-hydroxycoumarin; Polychrome; Esculetin-6-glucoside; β-D-Glucopyranoside, 6-(β-D-glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
EINECS	266-499-1

Quality Control

Our Esculin is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. It is suitable for use as an analytical standard and in critical research applications. Comprehensive testing is performed, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.