Description

1-Benzyl-6-Hydroxy-7-Cyano-5-Azaindolin is a specialized azaindole derivative, a high-value heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzyl group, hydroxyl, and cyano substituents, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Its precise synthesis and high purity are critical for ensuring the success and reproducibility of downstream chemical processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a monomer or functional additive in the synthesis of advanced polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and as a reference standard.
• Fine Chemical Synthesis: Utilized for the custom manufacturing of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	1-Benzyl-6-Hydroxy-7-Cyano-5-Azaindolin
CAS No.	66751-31-3
Molecular Formula	C15H11N3O
Molecular Weight	249.27 g/mol
Synonyms	1-Benzyl-6-hydroxy-7-cyano-5-azaindoline; 7-Cyano-1-benzyl-6-hydroxy-1,5-dihydro-4H-pyrrolo[3,2-b]pyridin-4-one; 5-Azaindolin, 1-benzyl-6-hydroxy-7-cyano-; 1-Benzyl-6-hydroxy-7-cyano-4,5-dihydro-1H-pyrrolo[3,2-b]pyridin-4-one; 66751-31-3; Pyrrolo[3,2-b]pyridin-4(5H)-one, 1-benzyl-7-cyano-4,5-dihydro-6-hydroxy-
EINECS	Contact for details

Quality Control

Our 1-Benzyl-6-Hydroxy-7-Cyano-5-Azaindolin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.