Description

(E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid CAS NO 66735-65-7 is a high-purity, synthetically derived indole derivative featuring an acrylic acid moiety. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in the construction of more complex indole-based structures via reactions involving its acrylic acid functional group.
• Biochemical Research: Employed in the study of enzyme interactions and as a standard or reagent in biochemical assays.
• Agrochemical Development: Potential intermediate for creating novel plant growth regulators or crop protection agents.
• Material Science Research: Investigated for the synthesis of specialty polymers or organic electronic materials due to its conjugated system.

Basic Information

Product Name	(E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid
CAS No.	66735-65-7
Molecular Formula	C₁₃H₁₃NO₃
Molecular Weight	231.25 g/mol
Synonyms	(E)-3-(5-Methoxy-1H-indol-3-yl)prop-2-enoic acid; 3-(5-Methoxy-1H-indol-3-yl)acrylic acid; 5-Methoxyindole-3-acrylic acid; trans-3-(5-Methoxyindol-3-yl)acrylic acid; (E)-3-(5-Methoxyindol-3-yl)acrylic Acid; 66735-65-7; 5-Methoxyindole-3-acrylic Acid
EINECS	Contact for details

Quality Control

Our (E)-3-(5-Methoxy-1H-Indol-3-Yl)Acrylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports applications requiring reliable and traceable raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.