Description

1,1,1,3,3,3-Hexafluoro-2-(2,2,2-Trifluoro-1-Hydroxy-1-(Trifluoromethyl)Ethylphosphanyl)Propan-2-Ol is a highly fluorinated organophosphorus compound, valued for its unique chemical structure that imparts significant thermal and chemical stability. This compound serves as a critical advanced intermediate in the synthesis of sophisticated fluorinated materials and specialty chemicals. It is primarily sought by the pharmaceutical, agrochemical, and advanced materials sectors for research and development, as well as high-performance manufacturing processes.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing next-generation fluorinated pesticides and herbicides with improved efficacy and environmental profile.
• Ligand Precursor: Acts as a precursor for specialized fluorinated phosphine ligands used in catalysis, particularly for reactions requiring inert atmospheres.
• Advanced Material Research: Employed in the development of fluorinated polymers, coatings, and surfactants that demand high thermal stability and chemical resistance.
• Electrolyte Additive: Investigated for use as a high-performance additive in lithium-ion battery electrolytes to improve stability and safety.
• Organic Synthesis Building Block: Provides a versatile, fluorinated synthon for introducing trifluoromethyl and hexafluoroisopropyl alcohol moieties into complex molecules.

Basic Information

Product Name	1,1,1,3,3,3-Hexafluoro-2-(2,2,2-Trifluoro-1-Hydroxy-1-(Trifluoromethyl)Ethylphosphanyl)Propan-2-Ol
CAS No.	66644-46-0
Molecular Formula	C8H4F12O2P
Molecular Weight	400.08 g/mol
Synonyms	Hexafluoro-2-(trifluoro-1-hydroxy-1-(trifluoromethyl)ethylphosphanyl)propan-2-ol; 1,1,1,3,3,3-Hexafluoro-2-propanol, 2-[(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phosphinyl]-; Tris(trifluoromethyl)phosphine oxide derivative; P,P-Bis(trifluoromethyl)phosphinic acid hexafluoroisopropyl ester; (Hexafluoroisopropyl)phosphinous acid, O-ester with 1,1,1,3,3,3-hexafluoro-2-propanol; Fluorinated phosphinite alcohol
EINECS	Contact for details

Quality Control

Our 1,1,1,3,3,3-Hexafluoro-2-(2,2,2-Trifluoro-1-Hydroxy-1-(Trifluoromethyl)Ethylphosphanyl)Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 19F, 31P), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
19F NMR Purity	≥ 98.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.