Description

3-o-Propanoylmorphine is a specific morphine derivative, a compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key synthetic intermediate for exploring novel opioid receptor pharmacology and developing new analgesic agents. This product is essential for research laboratories, pharmaceutical development teams, and chemical manufacturers focused on neuropharmacology and controlled substance synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel opioid analgesic compounds and their prodrugs.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of morphine derivatives and their interaction with opioid receptors (μ, κ, δ).
• Reference Standard: Serves as a high-purity analytical standard for quality control and forensic analysis in laboratories handling controlled substances.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for understanding the biotransformation of related opioid compounds.
• Medicinal Chemistry: A substrate for the development of new chemical entities with potential modified efficacy, selectivity, or reduced side-effect profiles.

Basic Information

Product Name	3-o-Propanoylmorphine
CAS No.	66640-97-9
Molecular Formula	C23H27NO5
Molecular Weight	397.47 g/mol
Synonyms	3-Propionylmorphine; Morphine 3-propionate; 3-O-Propionylmorphine; 3-Propionyloxy-7,8-didehydro-4,5-epoxy-17-methylmorphinan-6-ol; Propionylmorphine (3-isomer)
EINECS	Contact for details

Quality Control

Our 3-o-Propanoylmorphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC-MS, and NMR. We adhere to cGMP principles for the production of research-grade pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.