Description

1H-Indole, 1-(Chloroacetyl)-2,3-Dihydro-3-Methyl- (9Ci) is a specialized indole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for targeted synthesis and scale-up projects. CAS number 66624-44-0.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides with specific modes of action.
• Fine Chemical Production: Serves as a precursor for complex dyes, pigments, and other high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials.

Basic Information

Product Name	1H-Indole, 1-(Chloroacetyl)-2,3-Dihydro-3-Methyl- (9Ci)
CAS No.	66624-44-0
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	1-(Chloroacetyl)-2,3-dihydro-3-methyl-1H-indole; 3-Methyl-1-(chloroacetyl)indoline; 1-Chloroacetyl-3-methylindoline; N-(Chloroacetyl)-3-methylindoline; 66624-44-0; Indole, 1-(chloroacetyl)-2,3-dihydro-3-methyl-; 3-Methylindoline-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole, 1-(Chloroacetyl)-2,3-Dihydro-3-Methyl- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for traceability and reliability in critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.