Description

5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is a significant heterocyclic organic compound featuring a fused indole and tetrahydropyridine structure. This molecule serves as a critical advanced intermediate in pharmaceutical research and development, particularly valued for its potential in modulating neurological and psychiatric pathways. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity building blocks for novel active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents.
• Neurological Research: Used in the synthesis of compounds targeting serotonin and related neurotransmitter systems for central nervous system (CNS) disorders.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Chemical Biology: Utilized as a probe or tool compound in biochemical assays to study specific biological targets and mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and APIs.

Basic Information

Product Name	5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
CAS No.	66611-26-5
Molecular Formula	C14H16N2O
Molecular Weight	228.29 g/mol
Synonyms	5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 4-(5-Methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridine; 5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridyl)indole; 5-Methoxy-3-(4-piperidinylidene)indole (tautomeric form); 66611-26-5; 5-MeO-3-(1,2,3,6-THP-4-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all relevant specifications and test results. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.