Description

Bicifadine Hydrochloride is a high-purity pharmaceutical intermediate and reference standard with the CAS registry number 66504-88-9. This compound is valued for its role in advanced pharmaceutical research and development, particularly in the study of analgesic mechanisms. It is primarily required by research institutions, analytical laboratories, and pharmaceutical companies engaged in the development of novel central nervous system (CNS) active agents and pain management solutions.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control, method validation, and regulatory compliance in analytical laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis and development of analgesic drug candidates.
• Neuroscience Research: Employed in preclinical studies to investigate mechanisms of action related to monoamine reuptake inhibition and pain pathways.
• Metabolite Studies: Utilized in the synthesis and identification of metabolic products for pharmacokinetic and toxicological profiling.
• Analytical Method Development: Acts as a key analyte for developing and optimizing HPLC, LC-MS, and other chromatographic assays.

Basic Information

Product Name	Bicifadine Hydrochloride
CAS No.	66504-88-9
Molecular Formula	C17H25NO2·HCl
Molecular Weight	311.85 g/mol
Synonyms	(±)-1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane Hydrochloride; Bicifadine HCl; (±)-Bicifadine Hydrochloride; Bicifadine Hydrochloride (racemic); L-060,562; Wy-47,011; CI-1004; DOV-21,947
EINECS	Contact for details

Quality Control

Our Bicifadine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.